• Ethylene oxide has been shown to cause lymphoid cancer and tumors of the brain, lung, connective tissue, uterus, and mammary gland in animals exposed to ethylene oxide by inhalation. Background: Cytogenetic changes associated with ethylene oxide (ETO) exposure at a worksite prompted a study of cancer incidence in that cohort. Name: Oxirane Ethylene oxide is known to cause cancer and other health issues. Ethylene oxide pollution has raised cancer risks for more than half a million people across the country, according to a Chicago Tribune analysis of EPA data. Cancer in Humans Epidemiological evidence of the risk for human cancer from ethylene oxide derives principally from the follow-up of 14 cohorts of exposed workers, either in chemical Ethylene oxide is an alkylating agent; it has irritating, sensitizing and narcotic effects. I know something about ethylene oxide. Abstr. The USEPA acknowledges that human data are insufficient to demonstrate that EtO causes any cancer in humans (e.g., lymphoid or breast cancer), even in workers exposed to levels up to millions of times higher than environmental levels to which the general U.S. population may be exposed. During my time at the US Environmental Protection Agency (EPA), I spent over 10 years on the team developing EPA’s cancer assessment of ethylene oxide, and for the last 5 of those years I was the project manager for the assessment. Is my breast cancer caused by ethylene oxide? exposed to ethylene oxide for more than 10 years (Teta et al. : 60 (1994) (p.73) CAS No. There is minimal cancer risk for the general population because most people are not exposed to significant quantities of ethylene oxide. In March 2020, the US Environmental Protection Agency’s Office of the Inspector General found that the agency had not done enough to inform people who are living near ethylene oxide–emitting chemical plants that they are likely to have an increased risk of cancer. 1. eCollection 2019 Oct-Dec. Ethylene oxide emissions by Vantage Specialty Chemicals in Gurnee and Medline in Waukegan are unacceptable. VOL. You may have a cancer claim for monetary damages caused by the medical plant that released the toxic ethylene oxide into the air. Gurnee, IL citizens demand clean air. The Occupational Safety and Health Administration’s (OSHA) ethylene oxide standard requires employers where ethylene oxide is present in the workplace to monitor employee exposure . After meeting with Trump, Medline wants FDA approval to sterilize N95 masks with ethylene oxide. ATLANTA — Another metro Atlanta company has been accused of - and fined for - spewing the cancer-causing gas ethylene oxide into the air. Ethylene oxide has been produced by a Swedish company since the beginning of the 1940s. See how people are Spreading Smiles across the Tennessee Valley Background: Ethylene oxide (ETO) is a sterilant gas considered to be a human carcinogen, due primarily to excess hematopoietic cancer in exposed cohorts. Sterilization Services … For decades, ethylene oxide (ETO) has attracted considerable research interest as a direct alkylating agent and likely human carcinogen. with ethylene oxide (IPCS-CEC, 2001). Residents near … (1) • … Studies show that long-term, occupational exposure to high levels of ethylene oxide increases the risk of breast cancer in women. Methods: We have studied breast cancer incidence in a cohort of 7576 women employed for at least one year and … 2. Elevated levels of the cancer-causing compound ethylene oxide were found in the air around two industrial plants last year near Smyrna and Covington. Ethylene oxide (EO), a direct alkylating agent and a carcinogen, can attack the nucleophilic sites of DNA bases to form a variety of DNA adducts. ETHYLENE OXIDE and OXIRANE Cancer Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments. ETO causes mammary tumors in mice, and has been associated with breast cancer incidence in one small epidemiologic study. 2019 Dec 11;17(4):1559325819888317. doi: 10.1177/1559325819888317. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Is the evidence for its carcinogenicity conclusive? Tumor type(s): Lymphoid cancer, (female) breast cancer (Steenland et al., 2003, 2004) Note: ADAF -- EPA has concluded that ethylene oxide is carcinogenic by a mutagenic mode of action. There is no single cause of, or risk factor for, breast cancer. International Agency for Research on Cancer (IARC) - Summaries & Evaluations ETHYLENE OXIDE (Group 1) For definition of Groups, see Preamble Evaluation. Well for starters, the National Cancer Institute describes the chemical used for it, ethylene oxide, as being “highly explosive and reactive” and they categorize it under cancer-causing substances (). Skip to main content Español 1-800-4-CANCER … Basis for listing ethylene oxide as known to the State to cause developmental toxicity, male reproductive toxicity, and female reproductive toxicity changed from Labor Code to 'Formally Required to Be Labeled or Identified' effective November 22, 2013. Vincent MJ(1 The International Agency for Research on Cancer classifies ethylene oxide into group 1. The World Health Organization). Suppose you know it’s bad for your health. Two other federal agencies are against it, citing cancer … Ethylene oxide (EtO) is a highly reactive chemical used as a sterilizing agent and a feedstock for producing other chemicals. This page contains the Ethylene Oxide DSD and background for the review. They threw out the EPA’s conclusion that cancer risks from ethylene oxide increase dramatically at lower levels of exposure and flatten out at higher concentrations. Articles from Occupational and Environmental Medicine are provided here courtesy of BMJ Group : 75-21-8 Chem. Contact Schneider Hammers’ legal team now for a … Ethylene oxide The Centers for Disease Control and Prevention yesterday released a draft toxicity profile of ethylene oxide (EtO) that treats it as a more far-reaching health threat than the Environmental Protection Agency does. Method: Cancer incidence through 31 December 1987 was ascertained in a cohort of 1132 individuals employed at the worksite at any time from 1 July 1974 through 30 September 1980, the period of potential exposure to ETO at the plant. Dose Response. Ethylene oxide was first discovered more than 160 years ago and signs of health risks from exposure to the gas date back 70 years. Ethylene Oxide: Cancer Evidence Integration and Dose-Response Implications. 1993) and elevated incidence of breast cancer in a cohort of workers who used ethylene oxide as a … Mikoczy, Zoli et al. The first study to establish a potential link between ethylene oxide and cancer was published in “Cancer incidence and mortality in Swedish sterilant workers exposed to ethylene oxide: updated cohort study findings 1972-2006.” International Journal of Environmental Research and Public Health 8, 6 (2011): 2009-19. Suppose you’ve ever heard of ethylene oxide. Chronic exposure to ethylene oxide is also mutagenic. 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